Bio-chemistry/Bio-medical
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Salmonella enterica Serovar Typhimurium Interacts with CD209 Receptors To Promote Host Dissemination and Infection
(American Society for Microbiology, 2019-07-23)Salmonella enterica serovar Typhimurium, a Gram-negative bacterium, can cause infectious diseases ranging from gastroenteritis to systemic dissemination and infection. However, the molecular mechanisms underlying this ... -
Loss of the virulence plasmid by Shigella sonnei promotes its interactions with CD207 and CD209 receptors
(Journal of Medical Microbiology, 2021)Introduction. Shigella sonnei, the cause of bacillary dysentery, belongs to Gram-negative enteropathogenic bacteria. S. sonnei contains a 210kb virulence plasmid that encodes an O-antigen gene cluster of LPSs. However, ... -
Genetic and phenotypic diversity of microsymbionts nodulating promiscuous soybeans from diferent agro-climatic conditions
(Springer Open, 2022)Background: Global food supply is highly dependent on feld crop production that is currently severely threatened by changing climate, poor soil quality, abiotic, and biotic stresses. For instance, one of the major challenges ... -
Genetic and phenotypic diversity of selected Kenyan mung bean (Vigna radiata L. Wilckzek) genotypes
(Springer Open, 2021)Background: Mung bean is a pulse crop principally grown in the tropic and subtropic parts of the world for its nutrient-rich seeds. Seven mung beans accessions from Eastern Kenya were evaluated using thirteen phenotypic traits. ... -
Effects of 2,4-D and Hexazinone Application on soil Dehydrogenase activity on Sugarcane Cultivated Soils in Nzoia Sugarcane Plantations, pp 361-371.
(2020-10)Diversity of flowering plants, pollinators and microbial activity was assessed in five farms of Nzoia Sugar Company and one outgrower farm in Western Kenya. The overarching study objective was to determine differences in ... -
Phenotypic Diversity Studies on Selected Kenyan and Tanzanian Rice (Oryzasativa L) Genotypes Based on Grain and Kernel Traits
(2015)Phenotypic characterization of rice (Oryza sativa L.) provides useful information regarding preservation of diversity and selection of parental genotypes with superior traits in plant breeding program. The main objective ... -
Nephrotoxicity effects of Khat (Catha edulis) on mice when administered orally
(2017-03)Renal problems are currently on increase worldwide. Some factors suspected to be the cause of the renal problems are drug abuse. Hence, this study investigated possible renal toxicity effect of ... -
In vivo Safety of Dichloromethane-Methanolic Extract of Allium sativum in Normal Mice.
(2017)The indiscriminate use of Allium sativum in treatment of various diseases can pose a great danger to various body functions. Assessment of the effect of the extract on haematological and biochemical parameters can be used ... -
Phytochemical screening and antipyretic activities of dichloromethanemethanolic leaf and stem bark extracts of Ximenia americana in rat models
(2017-07)Introduction: In most parts of Africa, Ximenia americana is used in folklore to treat various disorders such as oedema, pain, fever, helminthiasis, diarrhoea, burns among other diseases. This study tested the antipyretic ... -
Anti-inflammatory activities of dichloromethane-methanolic leaf and stem bark extracts of Ximenia americana in mice models
(2020)Introduction: Ximenia americana is a highly branched shrub mainly found in tropics of Asia, Africa, New Zealand, Central and South America among others. In most parts of Africa, X. americana is used in folklore to treat ... -
Antibiotic resistance in the sediments of a second order stream passing through agricultural farm land: Njoro river, Kenya
(2018)Abstract A significant proportion of the population living along River Njoro depend on direct river use to carry out domestic activities. Antibiotic pollutants in wastes of treated farm animals that have not undergone any ... -
Occurrence of Pathogenic Bacteria Harboring Antibiotic Resistant Genes in River Njoro in Nakuru County
(2018)Njoro River drains an agricultural catchment whose main livelihood activities are livestock rearing and employment in light industries. The limited quantities of piped water supplies coupled with inadequate sanitary ... -
Bacteriological quality and diarrhoeagenic pathogens on River Njoro and Nakuru Municipal water, Kenya
(2011-09)Waterborne diarrhoeal pathogens are considered a re-emerging threat and are responsible for considerable morbidity and mortality, especially in developing countries. The objective of this study was to determine bacteriological ... -
Analysis of Microbial Quality of Drinking Water in Njoro Sub-county, Kenya
(2019-10)Drinking water should be free of microbial pathogens so as to be regarded as potable water and safe for drinking. However, water is prone to fecal contaminants which are the sources of gastrointestinal illnesses. In Njoro ... -
Establishment of Reference Ranges for Liver Biochemistry Tests in Children in Meru County, Kenya
(2018-01)This study was aimed at determining the reference range values for eight liver function parameters that are routinely analyzed in the clinical chemistry laboratory of Meru Level 5 Hospital. The study was cross-sectional, ... -
Application on soil Dehydrogenase activity on Sugarcane Cultivated Soils in Nzoia Sugarcane PlantationsFoot-care influence on foot ulcer development among type 2 diabetes mellitus patients attending clinics in Embu.
(2019)Type 2 Diabetes Mellitus (T2DM) has become a global epidemic of 21st century with disproportionately high socioeconomic burden in the developing world. The prevalence of T2DM continues to rise resulting in significant ... -
Virulence Gene Markers and Multiple Drug Resistance in Escherichia coli Isolated from River Njoro in Kenya
(2012-11-29)The purpose of this study was to investigate the presence of Aeromonas hydrophila at commonly used water collection points on the River Njoro and to determine the in-vitro antimicrobial susceptibility and plasmid profiles ...